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Moreover shRNA-mediated knock-down experiments confirmed our observations by showing that silencing CXCR4 in NB cells impairs in vitro and almost abrogates in vivo growth.
Endotoxemia impairs in vivo and ex vivo MGU in addition to cardiac output.
Moreover, metformin impairs in vitro GBM CSC self-renewal, as measured by spherogenic activity.
Taken together, these findings demonstrate that genetic deficiency of PI3Kβ impairs in vitro development and resorptive function of osteoclasts.
Of note, we documented the reconstitution of miR-204 expression impairs in vitro and in vivo the tumor potential of GC cell lines.
The amount of accumulated damage increases with age due to impairs in the DNA repair system and an intensified oxidative stress and decreased antioxidant defense [ 14].
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For services to the Sight Impaired in Edinburgh.
At the same time, empathy and moral reasoning are lost or impaired in many psychopaths.
"A soldier with hearing loss is impaired in battle," Gates said.
This meant his fitness to practise had been impaired in Tomlinson's case.
For services to the visually impaired in Romania.
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