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Systematic analyses of E. coli fadR mutants collected in our laboratory in recent years allowed us to unexpectedly discover from K113 strain that a single point mutation (W60G) can impairs dramatically regulatory roles of FadR in lipid metabolism.
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This environment will surely induce a high delay variation and packet loss rate impairing dramatically the user experienced quality of conversational services such as VoIP.
We find that FAD PSEN mutations impair dramatically the fourth turnover in both Aβ49>Aβ40 and Aβ48>Aβ38 product lines, resulting in decreased Aβ40/Aβ43 and Aβ38/Aβ42 ratios.
Conversely, post-ischemic reperfusion impaired dramatically the production of NO but was not insensitive to EDTA pre-administration: in fact NO production following Isc/R in EDTA-pre-treated rats was similar to that measured in control rats.
Except the number, the morphology and structure of follicles were impaired very dramatically, and typical follicles were rarely found in the 85% PBS+3-MA group.
The absence of N-cadherin dramatically impairs short-term plasticity from facilitation to depression at glutamatergic synapses (Jüngling et al., 2006).
I'm no mental health expert, so I had to ask a basic question: What separates the clinical condition of social anxiety from the general anxiety that felt by everyone else? CEO Peter Shalek (at left in the photo above) said that with Joyable's clients, social anxiety "dramatically impairs their lives".
The same RNA, when delivered to rhombo-spinal precursors, stimulates ectopic expression of Emx2, whereas Emx2 knock-out dramatically impairs Emx2OS transcription.
For example, overexpression of Plk4 leads to centriole amplification; conversely, mutations or inhibition of the DmSAK/PLK4 gene dramatically impairs centriole duplication [10], [11].
We conclude that although pMOG vaccination does not affect IFN-γ production or lymphocyte infiltration into the CNS, it dramatically impairs subsequently induced MOG91 108-specific Th17 cell responses which correlates with protection froMOG91 108-specific
The scattershot allele results in an in-frame deletion of 8 amino acids at the junction of the third transmembrane domain and the second intracellular loop of Tre1 that dramatically impairs the function of this GPCR in germ cell migration.
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CEO of Professional Science Editing for Scientists @ prosciediting.com