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Perturbation of central signaling pathways, e.g., suppression of the nuclear factor kappa B (NF-kB), disrupts airway-branching and impairs development of epithelial, mesenchymal, and endothelial cell structures culminating in a failure of lung development [81 83].
It also impairs development of the lawyers' relationships with their clients.
Collectively, constitutive expression of Hes1 impairs development of thymocytes at several stages.
It has been suggested that obesity impairs development of the mammary glands both before and during pregnancy, but also endocrine, medical and psychosocial factors may play a role [32].
Here we show that the gamma-secretase and signal peptide peptidase (SPP) inhibitor LY411,575, but not the selective gamma-secretase inhibitor (GSI) DAPT, impairs development of P. berghei in vitro in hepatoma cells as well as in vivo in mouse liver.
Arsenic exposure impairs development and can lead to cancer, cardiovascular disease, and diabetes.
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The worm's larvae have been found in the brain, experts say, perhaps impairing development.
These results demonstrate that Runx1P1N/P1N mice exhibit markedly impaired development of basophils, but not mast cells.
Loss of placentally derived estrogen in preterm birth may impair development.
They see that certain plastics interfere with hormone systems, impair development and reproduction, and cause genetic abnormalities.
Acidification impaired development to the larval stage in H. tuberculata, but this was not the case for H. erythrogramma.
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