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Physical impairment and mental impairment were defined as significant impairment in daily life for more than one year due to disease, injury or symptoms.
Subtypes of cognitive impairment were defined as per the description of MCI by the Working Group of the European Consortium on Alzheimer's Disease [ 46].
In the presence of diabetes or kidney disease, hypertension was defined as blood pressure ≥130/8 0mm Hg. 26 Structural and functional renal impairment were defined as microalbuminuria (albumin creatinine ratio >2.0 mg/mmol in men and >2.8 mg/mmol in women) and estimated glomerular filtration rate <60 ml/min/1.73 m, respectively.
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Severe visual impairment was defined as visual acuity of 20/200 or poorer.
Mild visual impairment was defined as Snellen visual acuity of 20/25 to 20/40.
Functional impairment was defined as continued hospitalization, significant pain or limitation in performing daily activities, bed confinement, or coma.
Moderate visual impairment was defined as visual acuity poorer than or equal to 20/50 and better than 20/200.
Functional impairment was defined as having difficulty with one or more Activities of Daily Living [ADLs - bathing, dressing, feeding, toileting or transferring]); mobility impairment (difficulty walking several blocks); hearing impairment (a response of "poor" or "fair" to "Is your hearing excellent, very good, good, fair or poor?").
Renal impairment was defined as CrCl< 70ml/min.
Visual impairment was defined as binocular presenting VA <6/12.
Renal impairment was defined as eGFR less than 60 ml/min/1.73 m.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com