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Pterygium is a benign disease of the supporting orbital tissue that can cause impairment of visual function.
MAIN OUTCOME MEASURE: In the 776 patients who had explicit statements about impairment of visual function documented in their medical records, univariate and multivariable logistic analyses were used to assess the above relationship.
The loss of the clcn-7 gene is accompanied by severe impairment of visual function and atrophy in the neural retina, due to the loss of lysosome function in the neural retina and RPE [21], [32].
Elevated intraocular pressure (IOP) and long-lasting contact of the lens-iris diaphragm to the corneal endothelium eventually lead to corneal decompensation and severe impairment of visual function.
Importantly, impairment of visual function measured by OPs of the ERGs (Fig. 2), as well as ERK activation, the subsequent synaptophysin reduction and BDNF depletion after 1 month of diabetes, were all suppressed by lutein (Fig. 3).
In other cases, patients refer impairment of visual function that ranges from worsening of visual function in the morning due to the corneal decompensation at early stage to blurred vision and/or halos around lights due to glaucoma to a constant reduction in visual acuity.
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In this study we included patients >90 years old, who had significant bilateral cataracts causing impairment of visual functions not correctable by glasses (best corrected visual acuity [BCVA] worse than 0.7), or with unacceptable glare, polyopia, or reduced quality of vision attributable to cataracts.
Long-term deprivation of normal visual inputs can cause perceptual impairments at various levels of visual function, from basic visual acuity deficits, through mid-level deficits such as contour integration and motion coherence, to high-level face and object agnosia.
Compared with the general QoL evaluation tools, vision-related QoL measurements have been widely accepted as specifically reflecting the impact of visual function impairment on the individual.
According to the International Classification of Diseases (Update and Revision 2006) [ 20], there are four levels of visual function, namely normal vision, moderate visual impairment, severe visual impairment and blindness.
However, other aspects of visual function such as central visual field impairment may occur even on complete resolution of edema despite good VA [ 48, 49].
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