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In conclusion, the impairment of immune function caused by calving was more severe in cows in ≥3rd parity than in younger cows.
Infection by the human immunodeficiency virus (HIV) type 1 causes a chronic, progressive and eventually deadly impairment of immune function in humans [1].
Also, experimental studies on telomerase-deficient mutant mice show that antigen stimulation results in accelerated telomere loss in splenocytes and consequent impairment of immune function [21], and telomere dysfunction is associated with defects in organ regeneration after experimentally induced liver cirrhosis [22].
In addition, following the initial hyperinflammatory response, immune cell apoptosis occurs, taking part in the secondary impairment of immune function.
Impairment of immune function has been extensively demonstrated in previous studies to be associated with exposure to metals.
Patients with CLD are suffering from impairment of immune function due to significant reduction of both CD3+ and CD4+ lymphocytes.
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These findings support recent suggestions that UVR-induced impairment of immune functioning contributes to the aetiology of NHL.
Impairment of immune functions makes affected animals more susceptible to infectious pathogens and leads to an increased incidence of common calf diseases, e.g., enteritis and pneumonia [ 6].
It is tempting to speculate that the latter result may account for the known impairment of immune functions in patients with cancer.
After weaning there are alterations in the structure [ 7] and function [ 8, 9] of the piglet small intestine, changes in intestinal E. coli flora of piglets [ 10, 11] and impairment of immune functions in early-weaned piglets [ 12, 13].
Chronic stress has been associated with increased biological aging, suppression or abnormal regulation of immune function, impairment of brain structure and function, increased susceptibility to some types of infection and worsening of conditions like depression, heart disease and some types of cancer.
More suggestions(18)
loss of immune function
impairment of immune responsiveness
impairment of mucocilary function
impairment of renal function
impairment of immune defense
impairment of myocardial function
impairment of mucociliary function
impairment of immune competence
impairment of pancreatic function
impairment of immune response
impairment of immune tolerance
impairment of dopaminergic function
impairment of visual function
impairment of cognitive function
impairment of surfactant function
impairment of endothelial function
impairment of pulmonary function
impairment of immune system
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