Sentence examples for impairment of endothelial function from inspiring English sources
In another substudy of WISE it was shown that bed rest causes both mechanistic and functional impairment of endothelial function [ 26].
Acteoside was reported to protect cells from oxidative stress and free radical-mediated impairment of endothelial function (Chiou et al. 2004).
These observations were consistent with our previous finding that disruption of CD146 inhibits VEGF pathway in HUVECs (Jiang et al., 2012), providing an important clue for elucidating the precise molecular mechanisms responsible for the impairment of endothelial function, as well as disruption in tumor angiogenesis observed in CD146EC-KO mice.
At the very end of the disease stage, eNOS gene expression is decreased and contributes to the impairment of endothelial function [35], [38], [39].
Impairment of endothelial function assessed by FMD is already present at even prehypertensive blood pressure levels.
We hypothesized that exposure to increased ambient air pollutants results in further impairment of endothelial function.
Homocysteine has been implicated in cardio- and cerebrovascular disease, primarily through impairment of endothelial functioning, leading to atherosclerosis and thrombosis (16, 19– 22).
STZ treated animals performed poorly on MWM hence reflecting impairment of learning and memory behavior with a significant reduction in body weight, impairment of vascular endothelial function, and decrease in serum nitrite/nitrate levels, increase in serum glucose, aortic and brain oxidative stress levels and brain acetylcholinesterase activity.
NO destruction by free hemoglobin can also contribute to impairment of vascular endothelial function via transcriptional activation of adhesion molecules, including VCAM-1 and E-selectin, as well as potent vasoconstrictors such as endothelin-1 [ 19].
