It was reported that the antimicrobial mechanisms of Magnolia officinalis extract resulted mainly in cell membrane and wall damage, causing increased permeability of cell membranes or lysis of cell walls and loss of cellular constituents, impairment of structural components and changes in bacterial cell morphology [ 21], which could ascribed to ML and HL, the two main constituents of the plant.
component value: the metric that represents the RF impairment of a component.
This suggests that the lack of Stat3 activation in LIF-treated LM3 cells was due to a deficiency in LIF-R expression and not to the impairment of another component of the gp130/JAK/Stat3 signaling cascade.
Immunosuppression can be caused by impairment of any component of the immune system, which results in a decreased immune function and thereby leads to pathogen which cannot be effectively cleared and infection or tumor will occur [ 12].
Impairment of the physical components of quality of life have been found consistently in studies of gout patients [ 22, 24, 34, 35], and was notably related to the burden of symptoms and signs in this sample.
Increased transcriptional impairment of genes encoding components of mitochondria correlates with other indicators of increased stress in thorax cells, such as the upregulation of the stress responsive transcription factor jra (dJun) with many of its targets and the upregulation of proteasome subunits, which was also observed in flies submitted to oxidative stress [ 30].
Accordingly, numerous studies have demonstrated also that diabetes impairs vascular function via inhibition of the endothelium-dependent vasodilatation, accompanied by selective impairment of NO-dependent component of vasodilatation [ 6].
3 6 Association between metabolic syndrome and risk of developing cognitive impairment has been demonstrated in older women, with a 23% age-adjusted increase in the risk of developing cognitive impairment in the number of components of metabolic syndrome.
where X k represents the RF impairment of the kth component of a configuration, h k is a coefficient for the kth term, k=1,2,⋯,N, and Z represents the overall RF impairment of the configuration.
The subgroup of patients with monoarticular disease, a low number of attacks and an absence of tophi did not show any significant impairment of the physical component of the SF-36 when compared with that of the general population.
