The group's psychological profile indicated a higher prevalence of irrational fears (higher levels of neuroticism), possibly leading them to interpret small balance impairments as major deteriorations in balance control.
However, CBT has seldom been applied for primary prevention of health impairments or deterioration among working populations [ 13].
These impairments would cause synaptic deterioration, neuronal degeneration, and ultimately dementia.
Evidence from MMN topography [ 40, 41] and source modelling [ 42] has implicated frontal generator impairments in schizophrenia, and that in the early stages of illness there may be some further deterioration of these impairments reflecting illness-progression [ 42].
Clinically, it is also noteworthy that increased amyloid deposition has also been found to be associated with a more aggressive rate of cognitive deterioration and visuospatial impairments in DLB [ 21, 22].
The intracerebroventricular injection of either BM- or ASC-MSCs has been shown to increase lifespan and body weight, ameliorate motor function impairments, and slow the overall deterioration of twitcher mice, as model of Krabbe's disease (KD), by inhibition of the type of inflammation associated with KD progression [ 33].
Dysphagia or other feeding problems arising from neurological, cognitive or motoric impairments after stroke can give further nutritional deterioration [ 1- 4].
Later in the clinical course, she presented with worsening of her visual impairment with further deterioration of the vision in the left eye, again associated with elevated intracranial pressure.
Deterioration in IADL abilities, rather than cognition impairments, predicted a greater need of home help services in AD [ 88].
Mander, B. et al. Age-related impairments of memory and fast sleep spindles are mediated by deterioration of cortico-thalamic white matter pathways [abstract].
