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In the following review, common aspects of mitochondrial impairment concerned about neurodegenerative diseases are summarized including ROS production, impaired mitochondrial dynamics, and apoptosis.
This impairment concerned the recognition of the facial emotion expressions disgust, fear and anger.
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Almeida and Flicker [ 2] presented in their review several reports on the role of congestive heart failure in a generalized cognitive impairment, concerning memory and attention deficits.
Concerning the neuropsychological profile, the subtest analysis of the Wechsler IQ test showed impairments concerning processing speed and visual motor skills.
In addition, administrating the GDS-15 as an interview facilitates the completion of the questions for people with impairments concerning, e.g. vision.
At the beginning of the disease process patients display deficits of planning and strategical thinking, whereas in chronic patients this shifts towards impairments concerning categorization and flexibility as assessed by the WCST.
Visuospatial impairments concerning the left hemifield are represented by a relative preponderance of omissions and higher reaction time values in the left visual field compared to the right visual field, which results in positive values when calculating left minus right visual field performance.
Moreover, there is reluctance among physicians to prescribe anticoagulants in the elderly (due to cognitive and physical impairment concerns) [ 22], as well as for those with perceived bleeding risk or history of falls [ 23].
Patients could be included if they were 65 years of age or older, lived at home or in a non-medical institution, volunteered to participate to a periodic health examination and if a memory impairment concern was identified (either by the patient themselves or by a member of their family).
45 In most studies, disability or functional impairment is concerned with problems in any one or all three of these areas.
It is widely accepted that cognitive deficits in Alzheimer's disease (AD) are due, particularly as far as memory impairment is concerned, to the loss of central cholinergic neurons [ 1, 2].
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