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Nishimura, A. L. et al. Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration.
We assumed that the relationship between developmental coordination disorder and internalizing/externalizing problems in school-aged children is mediated by peer problems and tested the hypothesis that a greater degree of motor impairment causes a greater degree of peer problems and thus a greater degree of internalizing or externalizing problems.
However, the complexity of relationships among mental health conditions and work impairment causes difficulty in assessment.
We show that lysosomal enzyme impairment causes lysosomal vitamin B12 trapping.
However, it remains unclear if mitochondrial impairment causes organ dysfunction, is protective against impending organ injury or is an epiphenomenon.
The signaling impairment causes a failure to up-regulate DNA methyltransferase 1 (DNMT-1) during mitosis, so DNA methylation patterns are not completely copied from the parent to the daughter cells, causing demethylation and overexpression of genes that contribute to lupus flares (3).
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Thus, we examined whether the persistent retrieval impairment caused by dHipp nadolol microinfusions would provide protection against reinstatement.
Correctable vision impairment caused by refractive error is common in the United States population.
However, the potential brain impairment caused by chronic CCS abuse has not been reported previously.
Limited walking ability is the dominant functional impairment caused by LSS.
Thus, our study reveals a robust functional impairment caused by FMR1 mutations that might contribute to neuronal dysfunction in FXS.
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CEO of Professional Science Editing for Scientists @ prosciediting.com