Sentence examples for impairing virus from inspiring English sources

Future studies should focus on how CIITA can increase this ratio without severely impairing virus release as well the novel mechanism by which CIITA increases Gag-Pol levels.

Chloroquine, long used as an antimalarial drug, increases endosomal pH and acts as an antiviral agent by impairing virus release into the cytosol.

Inhibition effect of EGCG on the capacity to infect cells by several viruses has been reported by different authors, who found that EGCG inhibits entry of hepatitis C virus by impairing virus binding to the cell surface [ 88– 90].

Data presented here show that CAP remains bound to HIV-1 after removal of unreacted compound, impairing virus infectivity due to blockade of binding sites for cellular coreceptors CXCR4 and CCR5.

In addition to directly impairing virus replication, another effective protection mechanism used by multi-cellular organisms is to trigger suicide of the infected cell.

In conclusion, combination RASs R30Q/A92K enhanced virus production whereas other RASs impaired virus replication.

We found that deletion of the SIVmac239 nef gene significantly impaired virus release in cells expressing rhesus macaque tetherin.

In HIV producer cells, transient HLA-DR expression induces intracellular Gag accumulation and impairs virus release.

NIK-mediated nuclear relocalization of rpL10 is thought to trigger a defense response that impairs virus proliferation or spread.

The active kinase recruits and phosphorylates the downstream component rpL10 to propagate the defense-signaling cascade that impairs virus replication and/or movement.

Interestingly, we noticed two phenomena: i) CIITA did not induce intracellular retention of Gag or impair virus release in producer cells despite expression of HLA-DR and ii) the virus released from cells expressing CIITA was significantly more infectious.