Sentence examples for impairing the interaction from inspiring English sources

Generated problem: This defect may impair the user interaction with the system (e.g. lack of transitional utterance when switching from one scene to another, impairing the interaction sequence).

Second, impairing the interaction between Celf1 protein and rbpj mRNA with a "target protector" antisense morpholino yielded a moderate rbpj overexpression, both at the mRNA and protein levels, and recapitulated the segmentation defects.

The identification of genes responsible for the remaining elongation may allow us to test whether impairing the interaction between astral microtubules and the cell cortex leads to chromosome segregation defects.

Mechanistically, UXT binds to the promoters of the Notch signaling target genes and specifically interacts with the transactivation region domain of the Notch intracellular domain (NICD), impairing the interaction between NICD and the transcription factor RBP-Jκ endogenously.

In this study, we characterize the UXT protein as a novel repressor of Notch signaling in angiogenesis, which functions by impairing the interaction between NICD and RBP-Jκ/CSL.

Second, VP35 is phosphorylated by κB kinase epsilon (IKK-ε) and TANK-binding kinase 1 (TBK-1), thereby impairing the interaction of these kinases with their substrates IRF-3 and IRF-7 and preventing their phosphorylation [ 37].

Impairing the interactions between these proteins and PCNA by ATX-101 impairs the cellular DNA damage responses and thus sensitizes the cells to chemotherapeutic drugs [ 33– 33].

However, the incorporation of C60 slightly impairs the interaction between PEO and PVC.

In contrast, deletion of the similar region in the double helix did not impair the interaction between SNX6 and SNX1 (Figure 3c).

We found that loss of the first PBZ motif (PBZ1) remarkably reduced the total PAR-binding, whereas loss of the second PBZ (PBZ2) also impaired the interaction with PAR (Supplementary Figure 7A).

Extensive biochemical experiments confirmed the handshake bond in solution, and also revealed the molecular mechanisms underlying tip link malfunction in deafness: some mutations directly impair the interaction between protocadherin-15 and cadherin-23.