Sentence examples for impairing the function from inspiring English sources

A measure of the selective pressure acting on exons is the ratio of non-synonymous (potentially impairing the function of the gene) over synonymous (neutral) mutations.

Given the excessive accumulation of LDs in lysosomes2,4,5,26, they may exert membrane fluidization, hence impairing the function of central lysosomal membrane residents or protein complexes associated to the lysosomal membrane like mTORC1.

Consistent with this idea, we observed a reduction of a sign of DNA damage, dead stem cells, after impairing the function of BRM in the rpt5a mutant under normal B conditions (Fig. 7c).

In addition, old SCCs showed a higher ratio of non-synonymous (potentially impairing the function of the gene) over synonymous (neutral) mutations (Fig. 2d), meaning a higher number of potentially deleterious mutations compared to young SCCs.

Tumor-derived EVs can contribute to creating an immunosuppressive microenvironment by impairing the function of immune cells.

Unfortunately, the cascade of inflammation directly injuries intestinal epithelial tight junction permeability [3], particularly for tumor necrosis factor alpha (TNFα) and high-mobility group protein 1 (HMGby) [4], by impairing the function of mitochondria [5, 6].

The mucus also impairs the function of the cilia, the fine hairlike projections on cells that are crucial to cleaning the airways.

Excessive deflection should not impair the function of the structure or be aesthetically unacceptable.

Stress also can impair the function of the hippocampus, which is also involved in memory retrieval.

I later learned that I was retaining fluid, which impairs the function of the lungs, causing them to stiffen and compromising the transfer of oxygen into the blood.

As a rule, conditions that impair the function of an individual should lead to poorer survival in the long run and eventual dying out of the trait.