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Unfortunately, loss of rotation is observed when tuberosity excision is used, impairing function and patient satisfaction.
However, resistance is rarely considered in drug development and may inadvertently be facilitated, as many designed inhibitors contact residues that can mutate to confer resistance, without significantly impairing function.
Although the "one-to-one" drug design strategy has been successful in impairing function of targets associated with a number of diseases, recent reports of drug promiscuity, which are a potential source of adverse reactions in patients, make a case to refine the drug design strategy such that it includes an awareness of multiple interactions from both ligand and protein perspectives.
These conditions can limit the range of motion of the affected joint, thereby impairing function and ability to perform activities of daily living.
Common symptoms include pain, swelling, and stiffness, can limit the range of motion of the affected joint, thereby impairing function and ability to perform activities of daily living.
While worm and mouse AH domains are two of the most divergent among published complexin sequences, the two domains could be exchanged without impairing function in vivo.
Similar(51)
This alters movement patterns and impairs function.
Too much cortisol can impair function and hinder focus.
Tooth extraction induces residual ridge resorption which impairs function and aesthetic of dental prostheses.
A tumor on or near the spinal cord can disrupt this communication, impair function and seriously threaten health.
Results suggest that adults with HIBM have profound muscle weakness and impaired function.
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CEO of Professional Science Editing for Scientists @ prosciediting.com