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Priming was achieved in 8 out of the 11 donors examined (Figure 2C), and reasons for the failure to induce priming in all donors are unknown, but may include the death of newly activated T cells, the HLA differences among donors, or even T cell impairing effects exerted by the virus on the immune cells from some individuals.
Investigations into the pathophysiology of coagulation impairing effects of hyperosmolar solutions are rare.
Such effects could well explain impairing effects of GCs on consolidation occurring during sleep (Born and Wagner, 2004).
The motor impairing effects of L-745,870 are most likely due to the antagonist binding to D2 receptors, when the drug level in the brain is high [ 13].
In alcohol nonpreferring rats, acute tolerance to the motor impairing effects of ethanol develops within 60 90 min following an i.p. injection of 2 or 2.3 g/kg ethanol.
While GCs have been consistently shown to impair retrieval (de Quervain et al., 2000, 2009; Wolf, 2009) we observed either enhancing or impairing effects depending on whether animals were asleep or awake during the retention interval.
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We note that first, there is substantial evidence to suggest that midazolam has a far greater proportional impairing effect on explicit than implicit memory [ 35- 38].
Figure 10: Impaired effects of GW9508 on FGF21-null brown and beige adipocytes.
But exercise did not improve the impaired effects of simulated microgravity.
It causes large errors, broken edges, and other visually impaired effects.
Stress induction is thus suggested to have a general impairing effect on the reconsolidation of fear memories.
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