Sentence examples for impaired viability from inspiring English sources

MTT assay demonstrated that none of the treatments impaired viability (+55%, p = 0.04) (Figure S5).

This finding is in agreement with previous reports that found fully differentiated effector T cells had impaired viability [26].

Male germ cells in mice lacking suv39h, which synthesizes H3K9me3 in pericentric heterochromatin, display severely impaired viability and chromosomal instability [22].

H3K9m3 is associated with pericentromeric heterochromatin and crucial for proper mammalian development, as mutants in H3K9m3 histone methyltransferases, Suv39h1 and Suv39h2, display genomic instability and impaired viability [3] [5].

By contrast, IMAs neither accumulated MPP+ nor displayed impaired viability in response to up to a 120 μM concentration of extracellular MPP+.

Doses of 0.1 and 0.2 mg/kg/day were chosen because they straddle the threshold for barely detectable cholinesterase inhibition and the first signs of reduced weight gain or impaired viability (Slotkin et al. 2006a, 2006b).

Disruption of MAS has been reported to impair viability and fetal growth in mouse blastocysts [36].

It was found that the loss of HslU2 does not impair viability, even though a reduced growth of the promastigote stage was observed.

These data correlate well with the potency of the respective shRNA to decrease GSH levels and to impair viability in vitro (Suppl. Fig. 1).

Consequently, perturbation of this equilibrium by depletion of RUNX1/ETO leads to loss of self-renewal, whereas knockdown of RUNX1 severely impairs viability (Ben-Ami et al., 2013; Dunne et al., 2006; Martinez et al., 2004; Martinez Soria et al., 2009).

Moreover, in view of the increased level of apoptosis in circulating DCs in patients with cancer described here, it is tempting to speculate that pro-apoptotic tumor products that regularly gain access to the peripheral circulation at high concentrations, such as IL-10 and gangliosides [ 30, 31], could potentially impair viability of blood DCs in vivo [ 2].