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Other studies with similar results [ 11, 13, 21] interpreted this performance as a poor ability of SF6D to distinguish severely impaired status.
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Other exogenous factors such as being retired or unemployment and prior psychiatric history were also related to depressive symptoms, as were poor functional status, impaired cognitive status, and respiratory illness.
Finally, patients at a terminal stage (stage D) who have very impaired physical status (performance status test score >2) or tumor burden (stage D) should receive symptomatic treatment.
ICU-AW is associated with short-term and long-term physical impairments and impaired functional status [ 1].
Considering the high rate of comorbidities, impaired nutritional status, and impaired functional status of patients with recurrent and/or metastatic HNSCC, they should be treated with less toxic strategies.
Furthermore, age, lower functional status before hospital admission, impaired cognitive status, depression and prolonged length of hospital stay are significant predictors of hospital related functional decline in elderly patients [ 3- 5].
Impaired health status may lead to impaired quality of life, but this is not always the case [ 21].
Interruption of the methylation cycle resulting from impaired folate status or deceased vitamin B12 or vitamin B6 status may have serious long-term risks.
Finally, poor SQ has been linked to pre-RTx impaired health status [ 14, 15], with post-RTx health status improving alongside SQ [ 13, 16].
DISCUSSION: Co-existent sensory and cognitive impairments were associated with higher risk of impaired functional status.
Patients with highly impaired performans status (Karnofsky score below 50) or with highly impaired nutritional status could be ineligible to carboplatin.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com