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By the recording and analysis of electrophysiological and biomechanical parameters during a functional movement such as locomotion, the significance of, for example, impaired reflex behaviour or pathophysiology of muscle tone and its contribution to the movement disorder can reliably be assessed.
Such a disability could result from impaired reflex development, which we speculate is related to perturbed brain function in PEX13 brain mutants.
In utero exposure of children born in an area of major agricultural production was associated with impaired reflex functioning, particularly in those assessed after 3 days postnatal [ 49].
In the CHAMACOS cohort study, including women resident in an area of major agricultural production, the presence of the OP metabolite dialkylphosphate (DAP) in maternal urine or blood was associated with impaired reflex functioning in infants after PND 3 [ 20].
Both your body and brain slow down when you're sleepy, resulting in impaired reflex reactions.
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Sleep deprivation causes irritability, poor cognition, impaired reflexes and response time (think: car accidents!), and chronic sleep deprivation can contribute to depression and anxiety.
It also has strong backing from medical and highway-safety experts, who note that a blood alcohol level of.08, though still producing impaired reflexes, is preferable to a level of.10, the limit in many states.
We show here that LTβR deficient mice did not develop ECM and survived more than 20 days, while C57BL/6J wild type mice developed typical neurological signs of CM, including postural disorders, ataxia, impaired reflexes and loss of grip strength, progressive paralysis and coma, and succumbed within a week after infection with 5 10% of parasitized erythrocytes (Figure 1A).
This is not surprising, given their immobility and often impaired reflexes, putting them at risk for medical crises.
Data on clinical presentation including neurological signs and altered sensation, impaired reflexes and pain radiation pattern were recorded by the clinician at the first appointment.
Furthermore, eccentric exercise may impair reflex activity which could lead to compromised joint stability during perturbations [ 43, 80].
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