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Ten-year follow-up assessment of this population found that despite a very low prevalence of tobacco smoking, 41% had persistently impaired pulmonary function, most commonly restrictive impairment.
Several studies have found associations between diesel exposure, respiratory symptoms, and/or impaired pulmonary function.
3R4F smoke induced the typical adaptive changes in the airways, as well as inflammation in the lung, associated with emphysematous changes (impaired pulmonary function and alveolar damage).
Enteral tube feeding (ETF) is widely used in patients with cystic fibrosis (CF) and end-stage lung disease, but previous studies have been limited to investigating whether ETF improves outcomes in patients with moderately or mildly impaired pulmonary function.
These studies have suggested that this therapy is safe, is at least as effective as intermittent nebulization, and may be superior to intermittent nebulization in patients with the most severely impaired pulmonary function.
Impaired pulmonary function, ineffective cough and difficulty mobilising secretions place SCI patients at increased risk for atelectasis and aspiration.
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As a consequence, a protein-rich lung edema develops and impairs pulmonary function [ 1].
Considering that RFA seems to impair pulmonary function less than SBRT inducing radiation pneumonitis, RFA may be applied to the patients with severe pulmonary dysfunction.
Although not the subject of the present study, there is evidence from studies described below that such extrapulmonary organ damage can impair pulmonary function.
Any change occurring in one component of the mucus-cilia unit might lead to disruption of normal mucociliary clearance processes, reducing lung defences and allowing respiratory secretions to accumulate and impair pulmonary function [ 4].
When disruption of normal secretory or mucociliary clearance processes occurs, respiratory secretions can accumulate and impair pulmonary function, reduce lung defenses and increase the risk for infection and possibly neoplasia [ 14].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com