Sentence examples for impaired progression from inspiring English sources

Given that overexpression of hCdc14B impaired progression through mitosis, we next analyzed the mitotic phenotype caused by ablation of hCdc14B.

A decrease of cells in G2 phase could indicate impaired progression through the cycle and, therefore, explain the observed cell viability reduction.

In proximal tubular cell cultures, HO-1 knockout cells had higher levels of basal autophagy, impaired progression of autophagy, and increased apoptosis with cisplatin administration.

At present, we surmise that NTBI toxicity impaired progression of T51B cells into or through mitosis, based on high levels of cyclin B1.

We reasoned that if the smc-5 and smc-6 mutant germ cells had impaired progression in DNA replication, then they should be less efficient in EdU incorporation, especially during short labeling periods.

Accordingly, imatinib mesylate has inhibited growth of ovarian cancer cells through PDGFRA and Akt inactivation (Matei et al, 2004), and combination therapy of imatinib paclitaxel has impaired progression of ovarian cancer in peritoneal cavity of nude mice and lead to increased apoptosis of tumour-associated endothelial cells (Apte et al, 2004b).

In one of the trials, the objective response rate was lower in dexrazoxane-treated patients, but it did not translate into impaired progression-free survival time.

This systemic response may impair progression of subsequent infections of neighboring mammary quarters [ 12, 17].

Depletion of CDC7 in cancer cells impairs progression through the S phase.

In summary, Trf1 deletion effectively impairs progression to full-blown carcinomas even in the absence of p53.

The swd mutation reduced exocrine pancreatic epithelial proliferation by impairing progression of cell division cycle and cell growth.