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Recently, double knockout mice for ZAS2 (Shn2) and ZAS3 (Shave have been generated, and they exhibit impaired growth plate maturation during endochondral ossification and massively elevated trabecular bone formation [17].
Inv rep uvrD recF cells were also impaired on MM; the plating defect was stronger for InvBE than for InvA, suggesting a possible replication impairment also at non- rrn sequences (MM, Figure 2A and B; Inv rep uvrD RecF+ colonies were not obtained).
As shown in Figure 7, LF82Δhfq growth was only slightly impaired on LB agar plates.
To test whether the self-renewal capacity of p63 +/L514F and Fgfr2b −/− cells was impaired, a secondary and tertiary plating strategy was employed.
As a consequence, necessary maintenance intervals are shortened and impaired technical components (e.g., plate or tube bundle heat exchangers) have to be replaced unscheduled.
In contrast, asb11cul embryos showed a smear of deltaA mRNA transcript across the neural plate, indicating an impaired Notch-mediated lateral inhibition.
Unexpectedly, stable silencing of HIF-2α also impaired NB4 CFU-L re-plating efficacy and slightly prolonged mice survival, although not affecting cell migration (Supplementary Fig S3B E).
We generated a lec-minus strain and confirmed its impaired lecithinase activity on egg yolk plates (Supplementary Fig. 6).
Likewise, germline development of smc-5 mutant animals is impaired when worms are grown on plates containing HU.
In addition, the ability to produce lipids in the tarsal plated of Bsg−/− mice was impaired compared with age-matched littermate controls.
Electroless plating of the Pd membrane impaired the catalytic performance of the deposited Ni/SBA-15 catalyst.
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CEO of Professional Science Editing for Scientists @ prosciediting.com