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Coexpression of certain sets of CDC37 mutants could promote Tax degradation through impaired physical interaction with Tax.
To gain insight into the biological relevance of the predicted and characterized Gli- and Sox-binding sites for rx2 expression in vivo, we introduced the same modifications that impaired physical interaction with the respective TFs.
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Impaired physical development could trigger a cycle of physical activity avoidance and reduced social interactions, which could lead to further reduction in physical fitness of obese children [ 9].
Other recent studies on HRQOL in older ICU survivors have reported impaired physical function [9, 28].
Patients with impaired physical functioning and muscle weakness were found to have reduced HRQL.
On the other hand, patients required long ICU hospitalization, may have impaired physical status and increased demand for FFP transfusion.
On the other hand, patients required prolong mechanical ventilation, may have impaired physical status and increased demand for FFP transfusion.
On the other hand, elderly patients may have impaired physical status and increased demand for FFP transfusion.
On the other hand, high severity grade patients may have impaired physical status and increased demand for FFP transfusion.
The interaction between an elevated core temperature and the pathological demyelination can cause a transient nerve conduction block that leads to temporarily impaired physical and cognitive function.
CS is an autosomal recessive progeroid disorder characterized by severely impaired physical and intellectual development.
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