Sentence examples for impaired organ function from inspiring English sources

However, elderly cancer patients often present with concomitant co-morbidities and age-associated physiologic problems, such as impaired organ function and functional changes that make the selection of optimal treatment difficult (Repetto and Balducci, 2002; Lichtman et al, 2007b).

This fluid overload is independently associated with impaired organ function, intra-abdominal hypertension (IAH), and poorer outcome [7 15].

Indeed, a positive fluid balance resulting from third spacing is independently associated with impaired organ function and worse outcome [7 11].

It frequently involves the lungs, eyes, lymph nodes, and skin; however, many of patients do not require treatment until they develop disability or impaired organ function.

The fact that a high fraction of HES solution is deposited in the tissues [10 14] might explain the impaired organ function.

Subsequently, sustained fibrosis leads to impaired organ function [ 3, 4].

Patients most at risk of harmful drug-herbs interactions are those at extremes of age, on multiple prescriptions, with chronic illnesses or with impaired organ functions and those on prescription medications with a narrow therapeutic margin, such as warfarin [23].

A common consequence of AGE accumulation is covalent cross-linking of AGEs to proteins, which leads to increased stiffness of protein matrix, impeding function and increasing resistance to removal of cross-linked proteins by proteolysis in various tissues and organs leading to impaired organ functions (Singh et al. 2001).

Aging impairs organ function.

These changes were less prominent in surviving animals and correlated with impaired mitochondrial and organ function.

An intra-organ defect in blood flow related to abnormal vascular reactivity, cell adhesion and coagulopathy may account for impaired organ oxygen regulation and function.