Sentence examples for impaired membrane function from inspiring English sources

It is due to this property of these constituents that the hepatoprotective activity of the extract is mediated by the normalization of impaired membrane function.

Insulin regulates the metabolism of β-amyloid and tau and dysfunctional insulin signaling has been linked to oxidative stress and mitochondrial dysfunction, resulting in disturbances of cellular glucose, acetylcholine, cholesterol and ATP levels, impaired membrane function, accumulation of β-amyloid and tau hyperphosporylation (Erol, 2008).

Statins are supposed to induce defective glycoprotein synthesis in muscle membrane, deficient chloride channel activation in muscle membrane and increased intracellular calcium leading to impaired membrane function, all leading to myocyte injury [29].

The severe germination problems reported in transgenic Brassica rapa seeds with elevated stearic acid content [ 39] might be associated with impaired membrane function due to the increased level of stearic acid in the membranes.

Increased intake of fatty acids may contribute to dementia through atherosclerosis and thrombosis, inflammation, impaired membrane functioning, or via accumulation of beta-amyloid (Kalmijn 2000).

COPs also impair membrane function, which results in altered membrane permeability [ 16].

The locally produced ROS oxidize the cell membrane phospholipids and generate lipid hydroperoxides which impair membrane function such as membrane transport, dysfunction of channel proteins, and loss of fluidity leading to tissue injury [3].

Lipotoxic effects impair membrane function and induce endoplasmic reticulum (ER) stress, mitochondrial dysfunction, inflammation, and cell death.

These effects, in turn, impair membrane function and induce endoplasmic reticulum (ER) stress, mitochondrial dysfunction, inflammation, and cell death.

Increased level of LPO impairs membrane function by inhibiting the membrane fluidity and altering the activity of membrane bound enzymes and receptors [ 48].

In addition, increased lipid peroxidation impairs membrane functions by decreasing membrane fluidity and changing the activity of membrane-bound enzymes and receptors.