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However, at 42 43°C, local toxicity impaired limb function dramatically.
If left untreated, the edema can lead to recurring infections, impaired limb function, psychosocial problems and, in extreme cases, malignant complications and life-threatening infections.
Approximately 15 million people suffer a stroke annually, up to 40% of which may develop spasticity, which can result in impaired limb function, pain and associated involuntary movements affecting motor control.
The residual impaired limb function and disability in the activities of daily living (ADLs) give stroke an important social impact: the recovery is partial in stroke survivors, with 15%30%% of patients permanently disabled and 20% requiring institutional care at 3 months after onset [ 3].
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Some of the reviewed studies found that people experienced impaired limb proprioception, or their sense of where their limb was in space after it had been iced.
IL-4 rs2070874 was significantly associated with phenotype of impaired limb mobility and fluid accumulation.
Among these children, between 50 70% have impaired upper limb function [ 2- 4].
This paper represents secondary analysis of a dataset from a cross-sectional study which aimed to screen for fatigue, impaired upper limb function, lymphedema, and pain in women following treatment for breast cancer.
Depending on the severity and extent of the OBPI, the overall quality of life of patients is very much affected due to impaired upper-limb function.
Patients frequently have persisting clinical problems including impaired upper and lower limb function, speech and cognitive problems, difficulties mobilising indoors, outdoors and on stairs, limited independence in self care, depression, and social inactivity [ 5].
Subjects with spinal cord injury had impaired upper and lower limb function bilaterally, a 30% reduced cord area, smaller white matter volume in the pyramids and left cerebellar peduncle, and smaller grey matter volume and cortical thinning in the leg area of the primary motor and sensory cortex compared with controls.
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