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In that study, all the patients investigated had functional impairment irrespective of psychopathology but those with psychiatric morbidity were differentially more impaired in terms of severity.
The PD patients were also found to be impaired in terms of their ability to synchronize the arm, hand, and torso.
In order to force S. cerevisiae to use galactose without respiration, a subunit (COX9) of a respiratory enzyme was deleted, but the resulting deletion mutant (Δcox9) was impaired in terms of galactose assimilation.
P2X2 receptors with K308A, K308C or K308R have been shown to be significantly impaired in terms of ion-channel function [ 7].
Compared with wild-type control cells, gankyrin null cells were impaired in terms of their proliferation, migration and anchorage-independent growth.
The Informant Only group was significantly more physically impaired in terms of ADL, sight (but not hearing or chronic illness) and had lower MMSE scores.
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NPY deletion did not alter the behavior or physiological response to CR. Leptin deletion impaired FAA in terms of some activity measures, such as walking and rearing, but did not substantially diminish hanging behavior preceding feeding time, suggesting that leptin knockout mice do anticipate daily meal time but do not manifest the full spectrum of activities that typify FAA.
We revealed impaired angiogenesis in terms of reduced branching and inhibition of proper EC migration owing to defective neural secretion in Tgfbr2-cKO, rather than defects in pericyte recruitment, endothelial cell proliferation or expression of cell junction proteins.
The German ProGERD study, for example, determined that patients with symptoms of GERD had substantially impaired HRQOL in terms of both physical and psychosocial aspects of well-being compared with the general population, and felt restricted as a result of food and drink problems, disturbed sleep, and impaired vitality and emotional well-being [ 5].
The present study was designed to identify factors leading HR older individuals to an impaired stepping performance in terms of frequency of maladaptive turning behavior (spin turn) and spatio-temporal patterns of fixations.
Besides muscle weakness, patients with OA have impaired sensorimotor function, in terms of sensory deficiency [ 7, 8], altered muscle activation patterns [ 9], and reduced functional performance [ 10].
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