"impaired effectiveness" is correct and usable in written English.
You can use it when you want to express that something's ability to work properly has been reduced or affected in a negative way. For example, "The outdated technology was causing impaired effectiveness in our online systems."
These are potentially examples of clients that have, at least partially, lost their dependency on Hsp90 and evade Hsp90 inhibition effects, which could impair effectiveness of cancer treatment.
However, response to analgesics and triptans can also change over time and depending on the frequency of usage (medication overuse headache impairing effectiveness of abortive medication).
It is established that iron corrosion in cast iron pipes: (1) causes increased turbidity, (2) impairs effectiveness of disinfectants due to their reaction with FeII (Kiéné et al. 1998; Zhang et al. 2008; Liu et al. 2014), and (3) causes increased roughness of the pipe's interior as a result of a corrosion scale that grows at the Fe0 surface.
"The costs to society of misconduct may be larger than the direct costs to customers and banks, particularly where it had impaired the effectiveness of the financial system," the Bank said its financial stability report.
In the District Court's view, the test was satisfied because respondents could have legitimately concluded that petitioners' relationship impaired their effectiveness on the job and that failure to discharge them would constitute tacit approval of an illicit relationship.
Vaccination seemed simple, but the vast number of persons who practiced it did not necessarily follow the procedure that Jenner had recommended, and deliberate or unconscious innovations often impaired the effectiveness.
Democratic leaders had prepared to hold a meeting on Thursday to determine whether they should strip Mr. Weiner of his committee assignments, which would have severely impaired his effectiveness.
Because headache disorders are most troublesome in the productive years (late teens to 60 years of age), estimates of their financial cost to society are massive — principally from lost working hours and reduced productivity because of impaired working effectiveness and absentees during attacks[28].
The negative effects predicted by [DADT] supporters -- mass resignations, declines in recruiting, degraded unit cohesion, impaired military effectiveness, decrease morale and disciplinary problems -- have yet to materialize.
