Exact(1)
Evidence for impaired construct validity was sought in a hierarchical regression analysis by investigating how much of the participants' FS-score variance was explained by the DKO-score, compared to the contribution of the knowledge level (NR-score), while controlling for Group, Gender, and Training length.
Similar(7)
The patients were impaired at constructing scenes relative to matched control subjects (replicated by Mullally, Intraub, and Maguire 2012) with a specific deficit noted in the spatial coherence of their imagined experiences.
This construct impairs the fusion of endocytic vesicles to the endosome, resulting in the accumulation of endocytic vesicles in the cytoplasm (Bucci et al., 1992) and the failure of trafficking from the early endosome (Zerial and McBride, 2001).
Separately, neither variation had a significant impact on protein function in the TA assay, but their presence in the same construct significantly impaired TA levels of the BRCA1 protein (Supplementary Figure S1).
Construct validity in this study relates to the hypothetical construct of impaired MC.
In contrast to wildtype and T400A/T404A/S408A-mutated occludin, a phospho-mimetic Occ-T400E/T404E/S408E construct was impaired in binding to ZO-2.
Proposed in 1988 by Reaven (1), the construct that impaired glucose regulation and insulin resistance to glucose stimulation frequently coexist with elevated blood pressure and dyslipidemia has been evolving into several diagnostic criteria of metabolic syndrome (2– 4), a well-established risk for development of cardiovascular events and type 2 diabetes.
This synthetic construct impairs translocation by raising a yet uncharacterized translocation barrier shown to be much less force dependent than the known unfolding barrier.
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