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IAH can increase airway pressures and impair ventilation.
For example, PM may impair ventilation in COPD patients by causing airway narrowing and increasing the work of breathing [ 8].
First, delivery of bicarbonate comes at the expense of an added sodium load that can contribute to hypervolemia and further impair ventilation [ 12, 13].
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In the case of a multiple fracture involving at least three consecutive ribs, a chest wall instability may occur that is associated with an impaired ventilation mechanism and increased risk of atelectasis (flail chest).
Airway plugging causes impaired ventilation, resulting in lower ventilation-to-perfusion ratios.
Secondary endpoints were fibreoptically assessed in situ position, occurrence of glottic narrowing, impaired ventilation, evidence of airway morbidity.
As a result, alveoli with relatively impaired ventilation are well perfused, leading to an increase in Va/Q mismatch.
Securing the position of the LMA-S before inflating the cuff reduced the incidence of airway morbidity, and of impaired ventilation due to glottic narrowing.
However, glottic narrowing impaired ventilation significantly more often in the control group with reduced tidal volume and/or increased maximum airway pressure.
It has also been demonstrated that hyperthyroidism is accompanied by a reduced muscle strength resulting in impaired ventilation under exercise [ 14, 15].
This caused impaired ventilation with tidal volumes of less than 6 ml.kg-1 in 13 of the 17 patients in the control group (77%) but in only five of the 13 patients (39%) in the study group (p = 0.04).
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