Specifically, our results show that perturbations of the competitive dynamics of a biophysical attractor network model through widespread membrane depolarization impair value-based decision making in a predictable way by modulating the susceptibility of network dynamics to background noise.
More generally, our simulation results provide an example for deriving mechanistically informed rationales for improving value-based decision making, as for example in populations that show impaired value-based decision making due to an increased randomness in choice behaviour as, for example, during healthy ageing41,42.
At the 12 month clinical test, 78.0% had normal glucose values and 19.8% had impaired values (IFG 6.5%, IGT 13.4%).
Out of 79 participants who had impaired values at baseline, five (2.2%) developed type 2 diabetes during the intervention and 42 (18.1%) reverted to normoglycemia.
Microsoft decided that it would still try to seek a friendly deal and that a hostile bid could impair the value of Yahoo.
Economic and demographic changes may severely impair the value of a home when it's time to sell, a decade or more in the future.
The citymaintains that "[t]here is nothing to suggest that preventing [petitioner] from prohibiting [the easements] will unreasonably impair the value of [her] property as a [retail store]." PruneYard Shopping Center v. Robins, 447 U.S. 74, 83 (1980).
But it is equally apparent that broad rules framed to protect the public and to preserve respect for the administration of justice can in their actual operation significantly impair the value of associational freedoms.
The agreement between the railroad company and the Mottleys must necessarily be regarded as having been made subject to the possibility that, at some future time, Congress might so exert its whole constitutional power in regulating interstate commerce as to render that agreement unenforceable, or to impair its value.
257, that a corporate franchise to take tolls on a canal could not be seized and sold under a fieri facias, unless authorized by a statute of the state which granted the act of incorporation; and that neither the lands nor the works essential to the enjoyment of the franchise could be separated from it and sold under such a writ, so as to destroy or impair the value of the franchise.
