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These differences may severely impair the interaction between dXNP and dDAXX.
Conformational changes in this area may therefore impair the interaction between CNA and CNB.
Lacking G9a did not impair the interaction between WIZ and GLP, suggesting that the interaction between WIZ and G9a might be indirect and mediated by the catalytic domain heterodimer of G9a and GLP.
Moreover, lacking G9a did not impair the interaction between WIZ and GLP, suggesting that the interaction between WIZ and G9a might be indirect and mediated by the catalytic domain heterodimer of G9a and GLP.
In response to DNA damage, phosphorylation by ataxia telangiectasia mutated and ataxia telangiectasia and Rad3 related at Ser15 and Ser37 can impair the interaction between p53 and MDM2, promoting the accumulation and activation of p53.
A conserved domain of RPGRIP1α1, the RPGR-interacting domain (RID), interacts with the RHD shared by RPGR1 19 and RPGRORF15, and some RP- and LCA-causing mutations in either RHD or RID were shown to impair the interaction between the two (Lu et al., 2005; Roepman et al., 2000a).
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However, the incorporation of C60 slightly impairs the interaction between PEO and PVC.
However, the deletion of the N-terminal PHD1KDM5B domain in KDM5B-N (i.e., KDM5B-N-△P) significantly impaired the interaction between KDM5B-N and the H3K4me0 peptide.
We show in our study that DRIL1 sumoylation impairs the interaction between DRIL1 and E2F1 in vitro (figure 5).
(D ) Down-regulation of G9a or GLP impairs the interaction between WIZ and ZNF644.
Together, these results suggest that Gly375 is essential for gephyrin receptor interaction and the replacement of Gly375 to aspartate severely impairs the interaction between gephyrin and GABAARs/GlyRs.
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