Sentence examples for impair the interaction from inspiring English sources

These differences may severely impair the interaction between dXNP and dDAXX.

To confirm the clathrin-independence, we blocked clathrin-mediated internalization with a dominant negative, GFP-tagged, mutant of Eps15, EpsΔ95/295, known to impair the interaction with clathrin adaptor proteins such as AP-2, and evaluated the effect on constitutive uPAR endocytosis.

Thus, both A98V and F124S mutations impair the interaction with FtsZ protein.

Conformational changes in this area may therefore impair the interaction between CNA and CNB.

The scanning activity of the ribosome may impair the interaction of the miRNA-RISC with the 5' UTR, suggesting there would be inefficient inhibition of gene expression.

Mutations at the E-cadherin extracellular domain may impair the interaction of E-cadherin and EGFR, lead to activation of EGFR, and further enhance cell motility through activation of RhoA [ 34].

The mutations in the active site of subtype AE directly impair the interactions with the inhibitor.

However, the incorporation of C60 slightly impairs the interaction between PEO and PVC.

Generated problem: This defect may impair the user interaction with the system (e.g. lack of transitional utterance when switching from one scene to another, impairing the interaction sequence).

However, the deletion of the N-terminal PHD1KDM5B domain in KDM5B-N (i.e., KDM5B-N-△P) significantly impaired the interaction between KDM5B-N and the H3K4me0 peptide.

In contrast, WDR21a, UVSSA, MCMBP, and MCM4 showed comparable USP7-binding affinity to M1USP7-FL, but impaired the interaction with W165AUSP7 (Fig. 2D), indicating that these proteins mainly bind to USP7 on the TRAF domain.