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In the current study, we observe that GBS has the capacity to impair the function and viability of cultured cardiomyocytes.
Fan LH et al. [ 22] proved that HF diet may impair the function and expression of KATP channels in vascular smooth muscle cells by patch clamp and western blotting, which provides powerful evidence for our results.
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Hypofunction of the mesolimbic dopamine system will impair the function of the mesocortical and nigrostriatal dopamine systems by influencing dopamine release and the cortico-striato-thalamo-cortical circuits that dopamine modulates.
DN constructs of GTPases can be unspecific and impair the function of other proteins [36], [37], [38], [39] and therefore should be used judiciously.
Thus, CYK-4E448K impairs membrane localization, and it is likely to impair the function of both its GAP and C1 domains.
Large increases in intracellular Ca2+ activate self-destructive enzymes, such as calpains and caspases, increase the production of free radicals, and impair the function of organelles [34], [35].
Acidemia has numerous negative physiologic consequences that impair the function of many different organs and body systems.
These mutations may impair the function of the resulting protein, and are thus rare in in vivo protein-coding sequences.
At the cellular level, the mutations may affect the polymerization of the lamins, disrupt the structure of the nucleus and impair the function of chromatin.
In this study, we further extend this research to show that H. pylori can multiply in BMDCs, and impair the function of BMDC.
From the previous literatures, it is clear that the strong combination between diabetes and renal dysfunctions and the diabetes impair the placental function and structure.
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