Exact(1)
These events subsequently trigger a cascade of pathological actions (so called secondary damage) including vascular and biochemical changes, hemorrhagic necrosis, inflammatory process and demyelination [1], [2], leading to a second wave of cell death and lesion area extension which impair the affected body functions.
Similar(59)
DOI: http://dx.doi.org/10.7554/eLife.10181.012 In contrast, we found that mutations impairing neurotransmission affected the odor responses of the ASEL and AWB secondary neurons, which we identified by cell ablation experiments.
These enzymes can induce haemorrhage, necrosis, oedema, skin damage, and inflammation, and degrade extracellular matrix components and impair the regeneration of affected skeletal muscle [ 6, 9, 15– 17].
Trying to ensure that changes to debt issues' terms were made in the light of day, the law states that debt holders' rights to receive interest and principal payments "shall not be impaired or affected without the consent of such holder".
Our results showed that transfection of human cells with artificial snoRNAs containing guide sequences directed to pre-mRNA could impair the splicing and affect overall mRNA isoform levels.
That therapy can actually impair the microcirculation and affect outcome was reported by Boerma and co-workers in a case study in a septic shock patient receiving the vasopressin analog terlipressin [ 49].
To explore this more systematically we determined how randomizing and/or shortening the TOG1-TOG2 linker in dimerization impaired Stu2p affected its rescue activity.
It has been suggested that the interaction between the truncated product of Mbf1 and Tbp is impaired, thus affecting the RNAP III dependent transcription of tRNA genes.
With vitamin D- or vitamin D-receptor deficiency, these immune responses are impaired and affected mice are susceptible to immune-mediated diseases of the intestinal tract [ 44].
In addition, impairments influence each other, i.e. impaired comprehension affects the repetition performance and vice versa.
Impairments in MMN accompanied by an unaffected P3a may suggest a subtle disruption in the initial automatic detection of change in the auditory environment that is not sufficiently impaired to affect the subsequent attention orienting response.
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