Exact(2)
AChE normally has a strong temporal association with the detection of novel or behaviorally significant stimuli and thus excessive AChE release might impair tasks that require learning novel stimuli [ 27, 28].
The configural learning hypothesis predicts that hippocampal damage will spare tasks solved by learning about single cues (elements), but impair tasks that demand the conjunction of cues for their solution (non-elemental or configural learning).
Similar(58)
Aspects of classroom lighting and décor that can promote discomfort and impair task performance through glare, and imperceptible 100 Hz flicker from fluorescent lighting, were examined in a sample of UK schools.
Given its ubiquitous function in cognition, distractor suppression should be particularly important under conditions where distractors impair task performance.
There is no guarantee that two lesions that each individually impair task performance will produce an additive effect when they occur together.
Theta burst stimulation of prefrontal cortex has been shown to impair task preparation [34], prospective memory [35], conjunction search [36], and behavioural updating [37], and reduce impulsivity in decision making [38].
Conversely, if early motor activity reflects neural processing necessary for perceiving body expressions, whereas motor resonance at 300 ms reflects an embodiment of the observed expression occurring after its visual recognition, we might expect that M1 stimulation at 150 ms but not at 300 ms would impair task performance.
This study does not identify the population of DG neurons that BDNF acts upon, but combined with the finding that knockdown of neurogenesis impairs tasks thought to depend on pattern separation (e.g., Clelland et al., 2009), one possibility is that BDNF acts on adult-born immature neurons in the DG.
Contrasting aphasic stroke patients with 'semantic aphasia' and patients with the semantic variant of fronto-temporal dementia, indicated that seemingly similar impairments are the result of impaired task-dependent access to semantic representations in the former group and degradation of the representations themselves in the latter group (Jefferies, 2006).
One's threshold for information overload that impairs task performance is dependent on the individual's working memory capacity (Unsworth & Engle, 2007), and this capacity is also known to be somewhat separable across verbal versus visuospatial domains (Shah & Miyake, 1996).
For example, subjects with high TAS-20 scores displayed impaired task performance on a signal-detection paradigm only under a time constraint condition, but not under a temporally luxurious condition [50].
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