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Thus, the piwi mutations impair regulation through a zygotic effect in TP5/NA females that already have a diminished capacity for regulation because they inherited their NA element from heterozygous mothers.
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"The central issue is impaired regulation rather than a simple 'deficit' as the name suggests; it's like the brakes in their brain don't work smoothly".
Other data suggested that some of the features of ASD may respond to fever and may result from impaired regulation of neurons in a region of the brain stem called the locus coeruleus.
The High Pb rats were also more sensitive to reward omission than controls, providing converging evidence for impaired regulation of arousal or emotion.
Metal dyshomeostasis is frequently observed in AD due to anomalous binding of metals such as iron (Fe), copper (Cu), and zinc (Zn), or impaired regulation of redox-active metals inducing the neuronal damage.
Some data suggests neuronal overgrowth potentially related to an increase in several growth hormones or to impaired regulation of growth factor receptors.
PKD2-depleted cells exhibit impaired regulation of muscle development-associated genes while the proliferative capacity remains unaltered.
Basonuclin-null mutation impairs regulation of corneal keratinocyte proliferation, which leads to perturbation in epithelium thickness and delay in wound re-epithelialization.
Alternatively, impaired regulation of the microcirculation might have resulted in shunting and thus high ScvO2.
This suggests that there is impaired regulation of blood flow in a significant subgroup of NTG patients.
An impaired regulation of both PAX6 and FOXE3 seems to be the cause of this abnormal phenotype.
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CEO of Professional Science Editing for Scientists @ prosciediting.com