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Considering that RFA seems to impair pulmonary function less than SBRT inducing radiation pneumonitis, RFA may be applied to the patients with severe pulmonary dysfunction.
Although not the subject of the present study, there is evidence from studies described below that such extrapulmonary organ damage can impair pulmonary function.
Any change occurring in one component of the mucus-cilia unit might lead to disruption of normal mucociliary clearance processes, reducing lung defences and allowing respiratory secretions to accumulate and impair pulmonary function [ 4].
Early clinical presentation of SSS often impacts skeletal growth and results in deformities such as scoliosis, a tiptoe gait, and a narrow thorax that can ultimately impair pulmonary function and lead to respiratory distress [ 84, 88].
When disruption of normal secretory or mucociliary clearance processes occurs, respiratory secretions can accumulate and impair pulmonary function, reduce lung defenses and increase the risk for infection and possibly neoplasia [ 14].
Although it is possible that people who are exposed to toilet bowl or air fresheners and other room deodorizers might also be exposed to cleaning products that impair pulmonary function, we had no data to address this.
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In contrast to other sedative/analgesic agents, dexmedetomidine does not impair pulmonary functions, even at high doses [ 13].
ALI induced by influenza may also lead to complications that severely impair pulmonary functions, and not only affect an individual's quality of life, but can also be life-threatening if left untreated [ 2– 5].
Ten-year follow-up assessment of this population found that despite a very low prevalence of tobacco smoking, 41% had persistently impaired pulmonary function, most commonly restrictive impairment.
Several studies have found associations between diesel exposure, respiratory symptoms, and/or impaired pulmonary function.
Impaired pulmonary function, ineffective cough and difficulty mobilising secretions place SCI patients at increased risk for atelectasis and aspiration.
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