Sentence examples for impair interactions from inspiring English sources
A series of Dox analogs with bulky substitutions at the C-4′ at amino-sugar have been designed to impair interactions between the drug and P-glycoprotein (P-gp), a multidrug drug resistance (MDR) transporter.
A possible explanation is the disrupted binding of αSyn-A30P to membranes that could impair interactions of αSyn with autophagosomes.
Phe GH5 mutations in human α globin include Hb Foggia (Phe117α- > Ser) exhibiting a phenotype typical of α thalassemia and was found to impair interactions with both β globin and the Alpha-Hemoglobin Stabilizing Protein (AHSP) [ 31, 32].
In contrast, mutations in the TFIIIB subunit encoding BRF1 gene (brf1 -II.6 and -II.9) that impair interactions of Brf1p with TBP (Andrau et al. 1999) showed a major shift to the longer extended transcript (lanes 4 and 5), with relatively little normal length RNA.
As such, information fraud can hurt the effectiveness of intelligent systems, impair interaction trust in the cyber world, and result in financial losses.
2, 3 The IMiDs possess antiangiogenic properties; 4, 5 impair interaction between malignant cells and bone marrow stromal cells; 6 induce cell cycle arrest; and have direct antiproliferative effects.
Mutations at invariant positions within each RPEL motif impair interaction with G-actin and de-repress the activity of the MRTF proteins (Miralles et al, 2003; Vartiainen et al, 2007; Guettler et al, 2008).
Furthermore, biochemical and cell-based analysis of Rab8A suggests that phosphorylation at Ser would impair interaction with its cognate guanine exchange factor (GEF), thereby preventing its activation (Figs 9 and 10).
Moreover, impaired interactions between mother(s) and children have been associated with long-term impairments in children's cognitive and emotional development [ 14].
A shift toward a proinflammatory status additionally impairs interactions between both cell types, affecting neurons, endothelial, or ependymal cells.
Finally, expression of the mutated form of 14-3-3ζ 14-3-3ζ 14-3-3ζinteractions of 14-3-3 whichimpairsdinteractions, stimulated neurite elofgation 14-3-3 14-3-3 14-3-3
