IFE-4 is expressed somatically, and its absence reduces neuronal and egg-laying gene expression, resulting in impaired egg laying (Dinkova et al., 2005).
Similar to defects seen in sie, mutations in cheerio impair proper egg chamber formation by directly preventing extension of centripetal processes and migration of FC around germ line cysts in the germarium (Li et al., 1999; Sokol and Cooley, 1999; Sokol and Cooley, 2003).
As a potential hypothesis for future study, conservation of N in eggs may impair offspring performance, constraining egg proteins to be nutritionally expensive.
Embryonic development was impaired in eggs originating from the contaminated site.
Hypomorphic mutations that impair EGF signaling result in a failure of vulval fate specification, resulting in a vulvaless animal that cannot lay eggs (the "bag of worms" phenotype) [ 15, 16].
We generated a lec-minus strain and confirmed its impaired lecithinase activity on egg yolk plates (Supplementary Fig. 6).
Depletion of Gwl from Xenopus egg extracts impaired checkpoint recovery, as judged by persistent activation of checkpoint proteins and delayed reactivation of Cdk1 after removal of DNA damage.
The elevation of the vitelline layer at the end of fertilization or InsP3 uncaging was often substantially impaired in these eggs.
White et al. [295] Chickens 5, 20, 40 mg/kg egg; before incubation Impaired hatching rate, high prevalence of splayed legs, and chicks with partial or complete loss of yellow pigment in the down n.r.r
In agreement, addition of 0.3 mM EGTA to the egg cytosol did not impair the bacteriolytic activity to E. coli, while addition of 0.5 mM EDTA to the cytosol significantly depleted its lytic activity to E. coli (Fig. 4).
