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Particular care, therefore, will be made in measuring the financial impacts of side effects.
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The impact of side effects of compression on improving visual acceptance and diagnostic performance (or speed of diagnosis), e.g. the smoothing of the noise in irreversibly compressed images can improve performance (and ideally should be factored out as a separate processing step from compression and utilized routinely if so).
Few were offered the opportunity to discuss the impact of side effects or the potential options available.
The large range of physicians' rating of treatment side effects is striking and indicates that doctors' views about the impact of side effects on health status vary substantially.
18, 62 The impact of side effects on quality of life must be taken into account since there has been no proven survival benefit.
As assessments were more frequent during interferon treatment in order to capture the impact of side effects, the results will be weighted toward the early months of treatment.
Interventions aimed at mitigating the impact of side effects on treatment adherence offer promise to help optimize treatment outcomes for the growing numbers of people living with HIV.
Interviews highlighted four themes surrounding decision making: perceived impact of side effects, the impact of others' experience on beliefs about tamoxifen, tamoxifen as a 'cancer drug', and daily reminder of cancer risk.
A randomised, double-blind crossover trial is underway to determine the effect of dexamethasone on nausea and vomiting, and the impact of side effects of dexamethasone and of nausea and vomiting on quality of life.
As most patients who discontinued GA did so because of side effects (73%), in non-completers the negative impact of side effects on HR-QoL may have outweighed GA's positive effect [ 29].
To minimize the impact of side effects occurrence on treatment withdrawals, the study design allowed dose reduction of lubiprostone when side effects occurred, at the discretion of the investigators, and redosing was performed in 17% of patients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com