Sentence examples for impacts of mutations from inspiring English sources

Visualisation of these interactions provides insights into the nature of molecular recognition events and has practical uses in guiding drug design and understanding the structural and functional impacts of mutations.

e.g. as training data for Machine Learning algorithms [ 36], so that tools that predict the impacts of mutations can be improved.

We show that the mCSM signatures can be used successfully to tackle different tasks related to the prediction of the impacts of mutations in proteins.

Tables from processed PDF files are converted into indistinct textual blocks, and in case they are reporting the impacts of mutations, our system detects them as impacts.

Thus, predicting the impacts of mutations in proteins is of major importance to understanding function, not only of molecules and cells but also of the whole organism.

For example, we can use several programs that predict the functional impacts of mutations, thus convert binary mutation values (e.g. stop mutation, substitutions, etc).

Thus, the computation of such energy landscapes offers a sensitive way to estimate the impact of mutations.

The impact of mutations on HRM scores was influenced by amplicon length and the position of the mutation within the amplicon.

The aim of this study is to evaluate the potential impact of mutations in the promoter region of the L ferritin gene on its transcriptional activity.

Currently, there are a number of protein modeling and docking tools that can be combined to evaluate the structural impact of mutations on drug binding, but for many biomedical researchers, using these tools would be a major challenge.

Therefore, the impact of mutations on the proteome might be strongly age-dependent.