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Implantation of a medical implant within the body inevitably triggers a host inflammatory response that negatively impacts its function and longevity.
3 This variation in position of the ECU tendon not only impacts its function, but also its relative stability.
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My laboratory focuses on understanding how changes in chromatin structure modulate its dynamics and impact its function.
Any changes to the primary, secondary, tertiary or quaternary structure of a protein can potentially impact its function, efficacy and safety.
In particular, recent mechanistic insight into the ways in which nanoparticles interact with the mononuclear phagocyte system and impact its function during homeostasis and inflammation have highlighted the potential of nanoparticle-based therapies for controlling severe inflammation while concurrently restoring peripheral immune tolerance in autoimmune disease.
However, an unintentional outcome of the migration from in vivo primary screens to highly target-specific HTS assays was a reduction in biological context caused by the separation of the target from other cellular proteins and processes that might impact its function.
These results suggest that early life stress can alter brain morphology and consequently impact its function.
If Ng is acting as a recruiting or targeting factor for CaM, its location within the spine may impact its function.
However, these approaches were insufficient to identify alterations in tumor suppressors (in which an alteration anywhere in the gene may impact its function) or the increasingly complex area of "long tail" hotspot alterations in oncogenes [ 10].
In this review, we will give an overview of the latest insights into the regulation of CPC localization and discuss if and how specific localization impacts its diverse functions in the dividing cell.
How does the localization of protein Y, a central innate immune adaptor, impact its function and its role in the antiviral response?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com