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Compared to cascade impactor analysis, laser diffraction is much faster.
Cascade impactor analysis is the standard technique for in vitro characterization of aerosol clouds generated by medical aerosol generators.
In this paper, the applicability of laser diffraction technology is evaluated as a very fast and highly reliable alternative for cascade impactor analysis.
Laser diffraction and cascade impactor analysis suggested high dispersion and deposition in the respiratory organs with a fine particle fraction of 31.2%.
Particle size distribution was determined gravimetrically by cascade impactor analysis using eight stages Marple personal cascade impactor (Sierra Anderson, USA).
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Next generation impactor (NGI) analysis indicated that the particles had a smaller aerodynamic size (MMAD ranging from 6 to 8.7 μm).
The residues were burned in a combustion chamber designed specifically for this purpose, and the smoke emissions were collected on 10-stage MOUDI impactors for analysis of PAH and total particle mass.
Additional in-line measurements were achieved with a multi-stage inertial impactor and by traditional analysis of ex situ product.
The LOD for the analysis of impactor samples was 0.01 ng/m.
The analysis of impactor data and the calculation of MMAD were performed as described by Thiel (2002).
The impact analysis of the glass fiber-reinforced polyamide showed that the impactor velocity has considerable effects on the impact response of the composite plates.
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