Treat: We aren't a drug company and we won't be running clinical trials, but there are two general areas that we want to impact initially.
The impact initially left him with no movement from the chest down, after he sustained fractures to vertebrae that severely compressed his spinal cord.
The appliances ruling had a huge impact; initially, 75% of fridges and freezers were rated G to D (low efficiency), but today 98% are classed A++ or A+++.
"It's going to be pretty small from a financial impact initially, but the range of ultimate outcomes for the iPad is pretty big," Mr. Sacconaghi said.
The impact initially causes necrotic cell death in the underlying tissue, followed by apoptotic cell death in the surrounding tissue due to multiple subsequent events, such as ischemia, excitotoxicity and altered gene expression.
"It won't make a significant impact initially," said chart company boss Martin Talbot, adding streams would account for "an uplift of about 10% in the Top 40".
It has no impact initially, until people start to see it and believe.
The impact initially caused a shift in public opinion that exerted great pressure for reform.
Add the fact that Google is selling its new smartphones at the same price as Apple's iPhone or Samsung Galaxy S7, and it will have a big struggle on its hands to make any impact — initially at least.
Psychological impact Initially, portable office units equipped with heaters housed the child-friendly and mother-and-baby spaces, but the inside of the motel is in reasonable condition, so some of the rooms have been repurposed as a longer-term solution.
Blavatnik also has a big financial bet going on chemicals company LyondellBasell that was initially impacted by the drop in oil prices last year.
