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Climate change has already begun to impact the structure and function of forest ecosystems in the Pacific Northwest by altering the frequency, intensity, and duration of droughts and heat stress, with implications for widespread environmental and socio-economic change.
In any case, many of the molecular effects of HDAC6 impact the structure and function of microtubules and actin filaments, both of which are critical to intracellular trafficking.
It is unclear if the differences in molecular mass impact the structure and function of vasoinhibins.
Overall, HSANs lead to neurodegeneration of the PNS, and the current working hypothesis is that HSAN1 is caused by mutations in subunits of SPT that impact the structure and function of the enzyme [ 29– 34, 348]48].
A secondary level of interpretation can identify those variants encoding a different amino acid or a premature stop codon likely to impact the structure and function of the proteins containing them.
Although the majority of the detected SNVs fall in non-coding regions (we refer to a non-coding region as any region that is not a protein-coding exon or a splice junction), a large number of them (56,016, or 22.3%) fall within protein-coding exons or splice junction sites, suggesting that SNVs have a huge potential to impact the structure and function of protein-coding genes.
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However, many exotic plant species have become established, potentially impacting the structure and function of native plant communities.
These physiognomic changes have impacted the structure and function of ecosystems in a number of ways.
How does sequence variation in DISC1 impact on the structure and function of the expressed protein?
The expansion of these elements has had a significant impact on the structure and function of primate genomes.
(33) The PolyPhen-2 program predicts a probable deleterious impact of the T448M substitution on the structure and function of RNF8.
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