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Rosiglitazone, a thiazolidinedione, has effects on insulin sensitivity and cardiovascular risk factors that may favorably impact the progression of coronary atherosclerosis.
There are a number of mechanical forces, aside from the change in compliance, that may impact the progression of cancer.
Nevertheless, whether SOX4 may impact the progression of NPC has not been detected.
Sirtuin inhibitors have also been developed, and many of them have been shown to impact the progression of neurodegenerative disorders or to exhibit anticancer activity.
This model mouse provides a tool to investigate how the presence of Hirano bodies may impact the progression of Alzheimer's disease and other neurodegenerative diseases.
Depressive symptoms can negatively impact the progression of MS, since depressed people with MS are less likely to adhere to immunomodulatory treatment [ 16].
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We tested if a commonly used analgesic (buprenorphine hydrochloride) would reduce pain and distress in these mice without impacting the progression of autoimmune disease.
As a multifaceted protein, BAG3 regulates many biological processes and impacts the progression of tumor in different ways.
All of these evidences indicated that the mechanisms of BAG3 in impacting the progression of tumor may involve the HIF-1 α signaling pathway.
Limiting tRNA isoacceptor pools during translation can have a significant, negative effect on the accuracy of translation by impacting the progression of ribosomes on mRNA, leading to ribosomal stalling or queuing, premature translational termination, translational frame-shifting, and amino acid mis-incorporation.
Anisimov's findings (i.e. metformin treatment started early in life significantly postponed tumor formation in female SHR mice) appear to agree with the idea that metformin's ability to impair the genesis of senescent cells (by decreasing their generation, enhancing their elimination, or both) negatively impacts the progression of age-related cancers.
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