Sentence examples for impact the differentiation of from inspiring English sources

Based on genome wide association studies that link obesity to the region on chromosome 10 that encompasses the TCF8 gene [9], [11] [13] and on the ability of ZEB1 to impact the differentiation of other mesenchymal cell lineages [15] [19], we hypothesized that ZEB1 opposes obesity.

CSF-1 is a secreted cytokine impacting the differentiation of hematopoietic stem cells into macrophages.

Hydrogen-terminated UNCD (H-UNCD) films were compared with standard grade polystyrene in terms of their impact on the differentiation of NSCs.

We found that, generally, the age of the individual animal had little impact on the differentiation of satellite cells.

Even with regard to the limited sample size this result suggests that spatial distance between the seed parents had no significant impact on the differentiation of the effective pollen pools received by each seed parent.

Results show that increased expression of Batf in T cells impacts signaling important to the proper development of thymic NKT cells and that the loss of Batf has a dramatic impact on the differentiation of CD4+, IL 17-producing T-helper cells (Th17) and T-follIL 17-producing cells (Tfh) in the periphery.

The histone acetyltransferase p300 significantly impacts on the differentiation of vascular SMCs underlining that chromatin remodeling is important for SMC phenotypic switching [ 69].

In agreement with this, a double knockout of FGF receptors 1 and 2 significantly impacted on the differentiation of OPCs and hindered myelin sheaths formation in a chronic cuprizone-induced demyelination model but not in acute demyelination in the same study [ 100].

If analysing subgroups of patients with malignant or benign tumours in view of the factor age, the criterion age under 30 years maintained the negative impact independently of the differentiation of the tumour.

These results are very different to those seen in muscle and prove that stress and tissue fluid micro-environments can greatly impact the differentiation and immunological properties of the engineered cartilage.

Here we demonstrate the impact of Sim1 in the differentiation of mDA and rostral 5-HT neurons using Sim1 gain- and loss-of-function experiments in vitro, and Sim1 deficient mice in vivo.