Sentence examples for impact specificity from inspiring English sources

The RBE and hairpins seemed unlikely to impact specificity as Rep2 and Rep5 have been reported to bind ITR2 and ITR5 interchangeably [10].

The term 'validated method' has a very specific meaning for bioanalytical measurements, and intra and inter-assay precision and accuracy, linearity, matrix impact, specificity, and stability under scenarios is required.

This strategy was used to maximize signal-to-noise and to identify and potentially correct for any subtle shRNA processing inconsistencies without significantly impacting specificity.

We discuss intricate relationships between distinct elements within complex regulatory landscapes and consider their potential impact on specificity and robustness of transcriptional regulation.

There is strong evidence that BCG tends to adversely impact TST specificity when it is given after infancy and/or repeated multiple times [22].

The ligand loading of HSA with uremic toxin predicts several key side chain interactions of site I that presumably have the potential to impact the specificity and impaired drug binding.

Our modeling showed that a G107S substitution can fit within the center of a CDR3β without substantially altering its overall structure, suggesting that a G107S mutation should not prominently impact fine specificity of pMHC recognition.

Position 482 is critical for substrate recognition by ABCG2, and mutations at this position significantly impact substrate specificity [17], [28].

However, mutation of this residue in ELF4-DBD to either glycine or alanine had no impact on specificity.

Using a slightly lower B value cut-off did compensate for this, but lowering the cutoff too far had a drastic negative impact on specificity.

UTP, GTP, and AMP binding studies were carried out for selected aptamers identically to the ATP studies to analyze the impact on specificity and selectivity.