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This showed that neither the introduction of the alkyne moiety nor of the Cy5-label between the peptide and PMO separated by an aminohexanoic acid spacer has any impact on the internalization activity of the peptide and the exon-skipping efficacy of the PMO.
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From the result, it can be clearly understood that surface morphology has a great impact on the cellular internalization capacity.
These results highlight the need to characterize the final properties of MNPs after protein adsorption in biological media, and demonstrate the impact of these properties on the internalization mechanisms in neural cells.
Based on a three-wave panel survey of 973 Flemish preadolescents (Mage = 11.15, SD = 1.13) we found that the motivational and self-evaluative components had a different impact on media internalization.
From these, we hypothesized that Cltc-mediated SPARC internalization has a negative impact on the anti-adipogenic effect of SPARC, and if so, it would be expected that suppression of Cltc in Skm-PCs may result in enhancing the anti-adipogenic effect of SPARC.
The realization of parents' authority is more and more dependent on the internalization of emotions in intergenerational interactions.
Importantly, there were no effects on the internalization of TfnR.
Since awd can also act on the internalization of surface receptor [ 21], we examined whether constitutive internalization of full-length Notch is affected in awd mutant cells.
Both interventions aim to encourage individual self-reflection on the internalization of Western beauty ideals.
Collectively, these results indicate that LRP1 expression directly impacts the internalization of FAM-Aβ42 in both neuronal and non-neuronal cells.
What was its impact on the country?
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